|Relatives|| Pa Spleen (husband)|
Bill-E Spleen (grandson)
|Book Universe||The Demonata|
|First Book Appearance||"Lord Loss"|
Ma and Pa Spleen are Bill-E's over protective grandparents. In Blood Beast, they are killed by Grubbs when he is struck with lycanthropy, but later revealed to have been killed by Juni Swan (or Nadia Moore).